Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904684 | 0.87 | RAB9A (0.39) | HRH3RAB9ALMNAMAPTKDM4E | |
| SCHEMBL7905860 | 0.85 | RAB9A (0.35) | HRH3RAB9ALMNAMAPTKDM4E | |
| SCHEMBL7902674 | 0.85 | HRH3 (0.40) | HRH3KDM4E | |
| SCHEMBL7896445 | 0.84 | KDM4E (0.34) | HRH3RAB9ALMNAMAPTKDM4E | |
| SCHEMBL7904622 | 0.84 | HRH3 (0.39) | HRH3KDM4E | |
| SCHEMBL7905953 | 0.82 | RAB9A (0.45) | HRH3RAB9ALMNAMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7908541 | 0.81 | RAB9A (0.44) | HRH3RAB9ALMNAMAPTKDM4E | |
| SCHEMBL7905274 | 0.80 | HRH3 (0.41) | HRH3KDM4ESMN1; SMN2SYK | |
| SCHEMBL7904733 | 0.77 | RAB9A (0.40) | HRH3RAB9ALMNAMAPTKDM4E | |
| SCHEMBL7902709 | 0.77 | SMN1; SMN2 (0.44) | HRH3KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |