Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896504 | 0.97 | HRH3 (0.39) | HRH3BACE1PTPN11ALDH1A1KDM4E | |
| SCHEMBL7896508 | 0.95 | HRH3 (0.41) | HRH3BACE1PTPN11ALDH1A1KDM4E | |
| SCHEMBL7896551 | 0.91 | CNR2 (0.36) | HRH3BACE1KDM4EMEN1KMT2A | |
| SCHEMBL7902674 | 0.88 | HRH3 (0.40) | HRH3PTPN11KDM4E | |
| SCHEMBL7904632 | 0.88 | HRH3 (0.41) | HRH3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7905274 | 0.87 | HRH3 (0.41) | HRH3PTPN11ALDH1A1KDM4E | |
| SCHEMBL7904622 | 0.87 | HRH3 (0.39) | HRH3PTPN11ALDH1A1KDM4E | |
| SCHEMBL7902706 | 0.87 | HRH3 (0.38) | HRH3ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7904007 | 0.85 | USP2 (0.40) | HRH3BACE1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7904665 | 0.85 | HRH3 (0.36) | HRH3BACE1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |