Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 17/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 16/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 12/20 | 0.45 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902838 | 0.84 | ITGB1 (0.43) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7906199 | 0.82 | ITGA4 (0.53) | ITGA4ITGB1ITGB7ITGA5 | |
| SCHEMBL7908715 | 0.79 | FNTA (0.33) | GPR132 | |
| SCHEMBL3835768 | 0.74 | ITGA4 (0.49) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7896744 | 0.74 | FNTA (0.34) | GPR132 | |
| SCHEMBL181376 | 0.74 | ITGB1 (0.65) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL181378 | 0.74 | ITGB1 (0.65) | ITGA4ITGB1ITGB7ITGA2ITGA5 | |
| SCHEMBL7905110 | 0.72 | GPR132 (0.37) | ITGA4GPR132 | |
| SCHEMBL7905108 | 0.72 | GPR132 (0.43) | GPR132 | |
| SCHEMBL7428248 | 0.70 | ITGA4 (0.76) | ITGA4ITGB1ITGB7ITGA2ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |