Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 19/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 19/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904105 | 0.85 | ITGB1 (0.58) | ITGA4ITGB1 | |
| SCHEMBL7908666 | 0.83 | ITGB1 (0.52) | ITGA4ITGB1 | |
| SCHEMBL7905112 | 0.82 | ITGA4 (0.45) | ITGA4ITGB1ITGB7ITGA5 | |
| SCHEMBL7428248 | 0.81 | ITGA4 (0.76) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| SCHEMBL7902836 | 0.78 | ITGA4 (0.35) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| SCHEMBL7905098 | 0.74 | ITGB1 (0.50) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7905121 | 0.73 | ITGA4 (0.42) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| SCHEMBL7428016 | 0.72 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| SCHEMBL4736989 | 0.72 | ITGA4 (0.77) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL6510331 | 0.71 | ITGA4 (0.57) | ITGA4ITGB1ITGB7ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |