Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896707 | 0.88 | GAA (0.45) | HDAC1ALDH1A1LMNAGAAALPI | |
| Phenylalanine SCHEMBL7906184 | 0.85 | SLC7A5 (0.52) | HDAC8ALPIPKMPTGS1XIAP | |
| SCHEMBL7904116 | 0.83 | SLC7A5 (0.45) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7906150 | 0.82 | SLC7A5 (0.43) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7906163 | 0.80 | L3MBTL1 (0.36) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19234913 | 0.80 | HDAC1 (0.62) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20715878 | 0.80 | HDAC1 (0.62) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5078465 | 0.80 | HDAC1 (0.62) | HDAC1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7896693 | 0.79 | ITGB1 (0.47) | — | |
| SCHEMBL6934867 | 0.79 | LTA4H (0.39) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |