Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GRB2 | P62993 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709242 | 0.89 | NOS3 (0.47) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL6934867 | 0.85 | LTA4H (0.39) | HDAC8 | |
| Phenylalanine SCHEMBL7906184 | 0.83 | SLC7A5 (0.52) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7906194 | 0.83 | ITGA4 (0.41) | ITGB3ITGAVITGB1ITGA2BMAPT | |
| SCHEMBL7896693 | 0.83 | ITGB1 (0.47) | L3MBTL1ITGB3ITGAVITGB1ITGA2B | |
| SCHEMBL7906197 | 0.83 | CCR2 (0.44) | ITGB3ITGAVITGB1ITGA2BOPRM1 | |
| SCHEMBL7905098 | 0.83 | ITGB1 (0.50) | ITGB1 | |
| SCHEMBL6932583 | 0.82 | PTPN1 (0.46) | ITGB3SLC7A5ITGA2BPTGS1ALPI | |
| SCHEMBL7906161 | 0.82 | GRB2 (0.47) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7908862 | 0.82 | ALDH1A1 (0.46) | ITGB3ITGAVITGB1ITGA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |