Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | TPH1 | P17752 | 10/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL7906184 | 0.91 | SLC7A5 (0.52) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7904116 | 0.89 | SLC7A5 (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL6931447 | 0.87 | CTSL (0.40) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7896737 | 0.86 | SLC7A5 (0.41) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL6935180 | 0.84 | DPP4 (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7906161 | 0.83 | GRB2 (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7902867 | 0.83 | SLC7A5 (0.39) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL6936891 | 0.82 | S1PR5 (0.47) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL7905124 | 0.82 | HDAC1 (0.45) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL6932583 | 0.82 | PTPN1 (0.46) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |