Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL28769591 | 0.97 | TSHR (0.43) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| Benzene SCHEMBL27867174 | 0.97 | TSHR (0.43) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| SCHEMBL28234421 | 0.95 | TSHR (0.41) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| Propane SCHEMBL27699488 | 0.93 | RAPGEF4 (0.47) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| Iodobenzene SCHEMBL27312427 | 0.87 | TSHR (0.40) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| Methyl Phosphonate SCHEMBL27299128 | 0.87 | CA1 (0.40) | RAPGEF4ALDH1A1KDM4EL3MBTL1TP53 | |
| SCHEMBL27531897 | 0.85 | MEN1 (0.36) | RAPGEF4ALDH1A1KDM4EL3MBTL1TP53 | |
| Phthalimide SCHEMBL28187520 | 0.82 | GSK3B (0.54) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL4533183 | 0.81 | TSHR (0.47) | TSHRACHERAPGEF4ALDH1A1KDM4E | |
| SCHEMBL475089 | 0.81 | ALDH1A1 (0.55) | TSHRACHERAPGEF4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6047 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490628-B | Preparation method of difluoroethanol compound | 五邑大学 | 2024-05-28 | — | — | CN | claimed |
| CN-114560837-B | Chromone compound and preparation method and application thereof | 五邑大学 | 2023-11-24 | — | — | CN | claimed |
| US-20230374006-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS LIMITED (CN) | 2023-11-23 | — | — | US | claimed |
| CN-112272661-B | Process for producing dicyclohexyl dicarboxylic acid diester and process for producing dicyclohexyl dicarboxylic acid | 富士胶片株式会社 | 2023-08-08 | — | — | CN | claimed |
| US-20230072265-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 4-({(1 R)-2-[5-(2-FLUORO-3METHOXYPHENYL)-3-{[2-FLUORO-6-(TRIFLUORO METHYL) PHENYL]METHYL}-4-METHYL-2,6-DIOXO-3,6DIHYDROPYRIMIDIN-1(2 H)-YL]-1-PHENYLETHYL}AMINO)BUTANOIC ACID OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2023-03-09 | — | — | US | claimed |
| US-20230047178-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS INC. (CN) | 2023-02-16 | — | — | US | claimed |
| EP-4099991-A1 | NOVEL PROCESSES FOR PREPARATION OF TEZACAFTOR | Laurus Labs Limited (IN) | 2022-12-14 | — | — | EP | claimed |
| CN-114901650-A | Formation of alpha-tocopherol from 2,3, 6-trimethylphenol | 帝斯曼知识产权资产管理有限公司 | 2022-08-12 | — | — | CN | claimed |
| US-20220227773-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2022-07-21 | — | — | US | claimed |
| CN-112010859-B | Fused ring compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-07-19 | — | — | CN | claimed |
| EP-0061313-A2 | Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics | PFIZER INC. (US) | 1982-09-29 | — | — | EP | claimed |
| EP-0052964-A1 | Adenine derivatives possessing pharmacological activity | BEECHAM GROUP PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| US-4332813-A | Allylsulfoxide enzyme inhibitors | MERCK & CO., INC. (US) | 1982-06-01 | — | — | US | claimed |
| EP-0008045-B1 | (1,2)-ANNELLATED 7-PHENYL-1,4-BENZODIAZEPINE DERIVATIVES AND SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Kali-Chemie Pharma GmbH (DE) | 1981-09-30 | — | — | EP | claimed |
| EP-0026307-A1 | Organic sulfoxides, process for preparing the same and pharmaceutical enzyme inhibiting compositions comprising the same | MERCK & CO. INC. (US) | 1981-04-08 | — | — | EP | claimed |
| EP-0025857-A1 | Organic sulfoxides having a latent allyl group, process for preparing the same and pharmaceutical antibacterial composition comprising the same | MERCK & CO. INC. (US) | 1981-04-01 | — | — | EP | claimed |
| EP-0024639-A1 | Organic sulfoxides having a latent allyl group, process for preparing the same and pharmaceutical enzyme inhibiting composition comprising the same | MERCK & CO. INC. (US) | 1981-03-11 | — | — | EP | claimed |
| US-4129572-A | TO STABILIZE POLYMERS USED IN FOOD PACKAGING INDUSTRY | LABAZ (FR) | 1978-12-12 | — | — | US | claimed |
| US-4102887-A | ANTIDEPRESSANTS, ANXIETY RELIEVING | AKTIEBOLAGET ASTRA (SE) | 1978-07-25 | — | — | US | claimed |
| US-3936429-A | Reactive polymer | FUJI PHOTO FILM CO., LTD. (JA) | 1976-02-03 | — | — | US | claimed |