SCHEMBL7905231

SCHEMBL7905231

CCOc1ccc(-c2cccc3ccccc23)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 1/20 0.65
CHRNA3 P32297 1/20 0.65
CHRNA7 P36544 1/20 0.65
PPARG P37231 9/20 0.56
PPARA Q07869 9/20 0.56
ENPP1 P22413 1/20 0.54
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
PPARD Q03181 1/20 0.52
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
NQO1 P15559 1/20 0.48
S1PR1 P21453 1/20 0.48
S1PR3 Q99500 1/20 0.48
LTA4H P09960 1/20 0.47
GUSB P08236 1/20 0.47
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28636259 0.87 CHRNB4 (0.70) CHRNB4CHRNA3CHRNA7PPARGPPARA
SCHEMBL25262526 0.87 CHRNB4 (0.51) CHRNB4CHRNA3CHRNA7PPARGPPARA
SCHEMBL19910981 0.83 CHRNB4 (0.48) CHRNB4CHRNA3CHRNA7KMT2AMEN1
SCHEMBL30963915 0.83 TP53 (0.51) CHRNB4CHRNA3CHRNA7PPARGPPARA
SCHEMBL6013603 0.83 NQO1 (0.64) KMT2AMEN1NQO1LTA4HNPC1
SCHEMBL4583516 0.81 CHRNB4 (0.46) CHRNB4CHRNA3CHRNA7KMT2AMEN1
SCHEMBL1890032 0.80 PPARG (0.56) CHRNB4CHRNA3CHRNA7PPARGPPARA
SCHEMBL16634411 0.80 PPARG (0.55) CHRNB4CHRNA3CHRNA7PPARGPPARA
SCHEMBL5698011 0.80 LTA4H (0.61) NQO1LTA4HNPC1TP53GAA
SCHEMBL3798335 0.79 CA12 (0.62) CHRNB4CHRNA3CHRNA7PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed