Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.70 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.70 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 9/20 | 0.53 |
| ▸ | PPARA | Q07869 | 9/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905231 | 0.87 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNA7PPARGPPARA | |
| SCHEMBL18255817 | 0.81 | CHRNB4 (0.56) | CHRNB4CHRNA3CHRNA7PPARGPPARA | |
| SCHEMBL1890032 | 0.78 | PPARG (0.56) | CHRNB4CHRNA3CHRNA7PPARGPPARA | |
| SCHEMBL9097183 | 0.77 | GAA (0.53) | CHRNB4CHRNA3CHRNA7CYP2C19CYP2C9 | |
| SCHEMBL16634411 | 0.77 | PPARG (0.55) | CHRNB4CHRNA3CHRNA7PPARGPPARA | |
| SCHEMBL20522283 | 0.77 | RAB9A (0.49) | CHRNB4CHRNA3CHRNA7CYP2C19CYP2C9 | |
| SCHEMBL28075369 | 0.77 | HTR1B (0.54) | — | |
| SCHEMBL3798335 | 0.76 | CA12 (0.62) | CHRNB4CHRNA3CHRNA7PPARGPPARA | |
| SCHEMBL9614088 | 0.76 | MAPT (0.47) | CHRNB4CHRNA3CHRNA7CYP2C19KDM4E | |
| SCHEMBL2056312 | 0.75 | CHRNB2 (0.62) | CHRNB4CHRNA3CHRNA7CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483474-B | Preparation method of 2-methylene-1, 3, 5-triaryl-1, 5-pentanedione | 上海应用技术大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-110483474-A | A kind of preparation method of 2- methylene -1,3,5- triaryl -1,5- pentanedione | SHANGHAI INST TECH | 2019-11-22 | — | — | CN | disclosed |