Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161785 | 0.81 | KDM4E (0.49) | LMNAKDM4EPOLBATMKCNMA1 | |
| SCHEMBL2108553 | 0.77 | CYP1A2 (0.40) | LMNAKDM4EPOLBATMMAOA | |
| SCHEMBL5204640 | 0.75 | — | — | |
| SCHEMBL2569547 | 0.74 | — | — | |
| SCHEMBL3699321 | 0.74 | — | — | |
| SCHEMBL18953099 | 0.74 | — | — | |
| SCHEMBL888653 | 0.74 | — | — | |
| SCHEMBL1656536 | 0.74 | MAOB (0.46) | LMNAATMMAOAMAOB | |
| SCHEMBL31688426 | 0.72 | KDM4E (0.51) | LMNAKDM4EPOLBATMKCNMA1 | |
| SCHEMBL28029054 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252139-B1 | TRIFLUOROMETHYLPYRROLE CARBOXAMIDES AND TRIFLUOROMETHYLPYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-03-31 | — | — | EP | claimed |
| US-7109150-B2 | Trifluoromethylpyrrolecarboxamides and trifluoromethylpyrrolethioamides as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-19 | — | — | US | claimed |
| EP-1105375-B1 | TRIFLUOROMETHYLPYRROLCARBOXAMIDES USEFUL AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-02-22 | — | — | EP | claimed |
| US-20040171490-A1 | Trifluoromethylpyrrolecarboxamides and Trifluoromethylpyrrolethioamides as fungicides | WALTER HARALD (CH) | 2004-09-02 | — | — | US | claimed |
| US-6699818-B1 | CONTROLLING INFESTATION OF CULTIVATED PLANTS BY PHYTOPATHOGENIC MICROORGANISMS | SYNGENTA CROP PROTECTION, INC. | 2004-03-02 | — | — | US | claimed |
| EP-1252139-A1 | TRIFLUOROMETHYLPYRROLE CARBOXAMIDES AND TRIFLUOROMETHYLPYRROLETHIOAMIDES AS FUNGICIDES | Syngenta Participations AG (CH) | 2002-10-30 | — | — | EP | claimed |
| US-6365620-B2 | Trifluoromethylpyrrolcarboxamides | SYNGENTA CROP PROTECTION, INC. | 2002-04-02 | — | — | US | claimed |
| US-20020019541-A1 | Trifluoromethylpyrrolcarboxamides | EBERLE MARTIN (CH) | 2002-02-14 | — | — | US | claimed |
| WO-2001049664-A1 | TRIFLUOROMETHYLPYRROLE CARBOXAMIDES AND TRIFLUOROMETHYLPYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-07-12 | — | — | WO | claimed |
| EP-1105375-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | Syngenta Participations AG (CH) | 2001-06-13 | — | — | EP | claimed |
| WO-2000009482-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-02-24 | — | — | WO | claimed |
| EP-2616459-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS I | BASF SE (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-9314030-B2 | Particulate wood preservative and method for producing same | KOPPERS PERFORMANCE CHEMICALS INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20150144027-A1 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME | KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) | 2015-05-28 | — | — | US | disclosed |
| US-20150056258-A1 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME | OSMOSE, INC. (US) | 2015-02-26 | — | — | US | disclosed |
| WO-2001049664-A1 | TRIFLUOROMETHYLPYRROLE CARBOXAMIDES AND TRIFLUOROMETHYLPYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-07-12 | — | — | WO | disclosed |
| EP-1105375-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | Syngenta Participations AG (CH) | 2001-06-13 | — | — | EP | disclosed |
| EP-1105375-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | Syngenta Participations AG (CH) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009482-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-02-24 | — | — | WO | disclosed |
| WO-2000009482-A1 | TRIFLUORO METHYLPYRROL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171490-A1 | Trifluoromethylpyrrolecarboxamides and Trifluoromethylpyrrolethioamides as fungicides | CBR3, CBR1, PYCR1 | LMNA 4838/4885KDM4E 694/4885POLB 2910/4885 |
| US-20020019541-A1 | Trifluoromethylpyrrolcarboxamides | CBR3, CBR1, DDT | LMNA 2380/4885KDM4E 421/4885POLB 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.