Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908140 | 0.85 | CA9 (0.52) | ALDH1A1GAAPOLBMAPTLMNA | |
| SCHEMBL7981937 | 0.84 | MAOA (0.54) | ALDH1A1GAAPOLBMAPTLMNA | |
| SCHEMBL5145645 | 0.77 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBMAPTMAPK1 | |
| SCHEMBL38659518 | 0.77 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBMAPTMAPK1 | |
| SCHEMBL11643369 | 0.76 | POLB (0.86) | ALDH1A1GAAPOLBMAPTMAPK1 | |
| SCHEMBL7908502 | 0.74 | PLA2G1B (0.37) | ALDH1A1GAAPOLBMAPTMAPK1 | |
| SCHEMBL7638276 | 0.74 | MEN1 (0.50) | ALDH1A1GAAMAPTMAPK1LMNA | |
| SCHEMBL7644918 | 0.74 | QPCT (0.45) | ALDH1A1GAAPOLBMAPTMAPK1 | |
| SCHEMBL16566454 | 0.73 | MAPT (0.78) | ALDH1A1GAAPOLBMAPTMAPK1 | |
| SCHEMBL36671102 | 0.71 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |