Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981937 | 0.86 | MAOA (0.54) | ALDH1A1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL7905397 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTGAAKMT2A | |
| SCHEMBL7639607 | 0.81 | TRPV1 (0.46) | — | |
| SCHEMBL7908502 | 0.78 | PLA2G1B (0.37) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL7644918 | 0.78 | QPCT (0.45) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL7638276 | 0.78 | MEN1 (0.50) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL7914787 | 0.75 | MYC (0.48) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL6186210 | 0.72 | HSD17B10 (0.49) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL7594773 | 0.71 | MAPT (0.52) | ALDH1A1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL7599729 | 0.71 | RAB9A (0.51) | ALDH1A1LMNASMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197803-B1 | VIRICIDES; PREVENTION REPRODUCTION | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-06 | — | — | US | disclosed |