Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897685 | 0.81 | HSD11B1 (0.38) | SIGMAR1HSD11B1HDAC4P2RX7OPRM1 | |
| SCHEMBL6897911 | 0.80 | ALDH1A1 (0.35) | SIGMAR1HSD11B1HDAC4TSHRP2RX7 | |
| SCHEMBL1782514 | 0.79 | KMT2A (0.39) | HSD11B1 | |
| SCHEMBL29508385 | 0.79 | KMT2A (0.39) | HSD11B1 | |
| SCHEMBL7081965 | 0.77 | HSD11B1 (0.34) | SIGMAR1HSD11B1HDAC4TSHRACHE | |
| SCHEMBL25312666 | 0.76 | PDE7A (0.36) | HSD11B1 | |
| SCHEMBL31164672 | 0.76 | PDE7A (0.36) | HSD11B1 | |
| SCHEMBL21981951 | 0.76 | PDE7A (0.36) | HSD11B1 | |
| SCHEMBL3132046 | 0.76 | ALOX5AP (0.40) | HSD11B1TSHROPRM1 | |
| SCHEMBL24058176 | 0.76 | MAPT (0.39) | TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616493-B1 | POLYMERISATION METHOD | UNIV COURT UNIV OF EDINBURGH (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-9018270-B2 | Method for producing polymers comprising multiple repeat units of bicyclic diamines | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2015-04-28 | — | — | US | disclosed |
| US-20130267616-A1 | Polymerisation Method | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2013-10-10 | — | — | US | disclosed |