Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NCF1 | P14598 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863962 | 0.75 | L3MBTL1 (0.61) | L3MBTL1KDM4EGAANCF1ACHE | |
| SCHEMBL27616510 | 0.74 | CYP1A2 (0.56) | PDE10AL3MBTL1KDM4EGAANCF1 | |
| SCHEMBL9006212 | 0.73 | MAOA (0.48) | KDM4EHPGDELANETSHRHSD17B10 | |
| SCHEMBL7828268 | 0.70 | PDE10A (0.56) | PDE10AGAAMEN1KMT2ALMNA | |
| SCHEMBL10855624 | 0.70 | TERT (0.56) | L3MBTL1KDM4EGAANCF1ACHE | |
| SCHEMBL14393692 | 0.68 | L3MBTL1 (0.69) | L3MBTL1KDM4EGAANCF1ACHE | |
| SCHEMBL7031171 | 0.66 | IGF1R (0.62) | — | |
| SCHEMBL2384919 | 0.66 | ALDH1A1 (0.51) | PDE10AL3MBTL1KDM4EGAANCF1 | |
| SCHEMBL31663100 | 0.65 | KMT2A (0.97) | L3MBTL1KDM4EGAANCF1MEN1 | |
| SCHEMBL14975993 | 0.64 | KDM4E (1.00) | L3MBTL1KDM4EGAANCF1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062559-A1 | SUBSTITUTED PYRAZOLOQUINOLINES AND DERIVATIVES THEREOF | SCHERING CORPORATION (US) | 2010-06-03 | — | — | WO | disclosed |