Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905274 | 0.87 | HRH3 (0.41) | HRH3KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7896508 | 0.86 | HRH3 (0.41) | HRH3KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7896445 | 0.86 | KDM4E (0.34) | HRH3KDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7905780 | 0.85 | HRH3 (0.40) | HRH3KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7902674 | 0.85 | HRH3 (0.40) | HRH3KDM4EATM | |
| SCHEMBL7896504 | 0.85 | HRH3 (0.39) | HRH3KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7904622 | 0.84 | HRH3 (0.39) | HRH3KDM4EALDH1A1ATM | |
| SCHEMBL7902706 | 0.84 | HRH3 (0.38) | HRH3KDM4EALDH1A1 | |
| SCHEMBL7904007 | 0.79 | USP2 (0.40) | HRH3KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7908482 | 0.78 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |