Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905780 | 0.91 | HRH3 (0.40) | BACE1KDM4EMEN1LMNAMAPT | |
| SCHEMBL7908481 | 0.89 | PIK3CB (0.44) | CNR2CNR1PIK3CBPIK3CAPIK3CD | |
| SCHEMBL7896504 | 0.88 | HRH3 (0.39) | BACE1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL7896508 | 0.86 | HRH3 (0.41) | BACE1KDM4EMEN1MAPTTSHR | |
| SCHEMBL7908545 | 0.86 | PRKDC (0.39) | PIK3CBPIK3CAPIK3CDPIK3R1AXL | |
| SCHEMBL7904007 | 0.85 | USP2 (0.40) | AXLBACE1KDM4EMEN1LMNA | |
| SCHEMBL7905773 | 0.81 | BACE1 (0.39) | AXLBACE1KDM4ELMNAHSD17B10 | |
| SCHEMBL7904622 | 0.80 | HRH3 (0.39) | PIK3CBPIK3CAPIK3CDPIK3R1KDM4E | |
| SCHEMBL7908500 | 0.80 | PIK3CA (0.41) | PIK3CAPIK3CDPIK3R1KDM4EAR | |
| SCHEMBL7902674 | 0.80 | HRH3 (0.40) | PIK3CBPIK3CAPIK3CDPIK3R1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |