Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905773 | 0.91 | BACE1 (0.39) | USP2KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7908545 | 0.87 | PRKDC (0.39) | USP2KDM4ETDP1LMNAPOLB | |
| SCHEMBL7905966 | 0.87 | CYP2D6 (0.49) | KDM4EALDH1A1TDP1HRH3KMT2A | |
| SCHEMBL7896504 | 0.86 | HRH3 (0.39) | KDM4EALDH1A1HRH3HTR2AHTR7 | |
| SCHEMBL7896424 | 0.86 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2HRH3KMT2A | |
| SCHEMBL7896551 | 0.85 | CNR2 (0.36) | USP2KDM4ETDP1HRH3KMT2A | |
| SCHEMBL7905780 | 0.85 | HRH3 (0.40) | KDM4EALDH1A1HRH3KMT2AMEN1 | |
| SCHEMBL7896508 | 0.84 | HRH3 (0.41) | KDM4EALDH1A1HRH3KMT2AMEN1 | |
| SCHEMBL7908481 | 0.83 | PIK3CB (0.44) | KDM4ETDP1HRH3KMT2AMEN1 | |
| SCHEMBL7902674 | 0.83 | HRH3 (0.40) | KDM4EHRH3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |