Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.43 |
| ▸ | FNTB | P49356 | 18/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910498 | 0.92 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7910209 | 0.90 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL7905174 | 0.82 | PPARG (0.40) | FNTAFNTB | |
| SCHEMBL7905941 | 0.82 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL7903902 | 0.78 | RAB9A (0.40) | FNTAFNTBKDM4EMAPTHPGD | |
| SCHEMBL7910598 | 0.78 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL7903834 | 0.77 | FNTA (0.43) | FNTAFNTBKDM4EMAPT | |
| SCHEMBL7903816 | 0.77 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7905477 | 0.77 | FNTA (0.49) | FNTAFNTBKDM4E | |
| SCHEMBL7910206 | 0.77 | FNTA (0.43) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |