Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919811 | 0.89 | NFKB1 (0.55) | NFKB1BLMPMP22SIGMAR1 | |
| SCHEMBL6586702 | 0.84 | FFAR1 (0.45) | PPARDPPARASIGMAR1FFAR1FFAR4 | |
| SCHEMBL7906188 | 0.81 | PDE4B (0.56) | NFKB1BLMPMP22SIGMAR1 | |
| SCHEMBL7914446 | 0.80 | NFKB1 (0.60) | NFKB1BLMPMP22PPARDPPARA | |
| SCHEMBL1966507 | 0.79 | NFKB1 (0.75) | NFKB1BLMPMP22PPARDPPARA | |
| SCHEMBL7148550 | 0.79 | NFKB1 (0.75) | NFKB1BLMPMP22PPARDPPARA | |
| SCHEMBL15921910 | 0.79 | NFKB1 (0.75) | NFKB1BLMPMP22PPARDPPARA | |
| SCHEMBL29633151 | 0.79 | NFKB1 (0.75) | NFKB1BLMPMP22PPARDPPARA | |
| Hydrochloric Acid SCHEMBL8904803 | 0.78 | BLM (0.76) | NFKB1BLMPMP22PPARDPPARA | |
| SCHEMBL7916052 | 0.76 | NFKB1 (0.61) | NFKB1BLMPMP22PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |