Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906188 | 0.79 | PDE4B (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7153263 | 0.76 | ADRA1A (0.75) | ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL12040566 | 0.69 | TDP1 (0.75) | TDP1L3MBTL1 | |
| SCHEMBL5966301 | 0.69 | TDP1 (0.75) | TDP1L3MBTL1 | |
| SCHEMBL1172674 | 0.69 | SLC2A1 (0.61) | TDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5663603 | 0.69 | HTR2A (0.61) | — | |
| SCHEMBL7919811 | 0.69 | NFKB1 (0.55) | — | |
| SCHEMBL1172476 | 0.69 | TDP1 (0.69) | TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL7144089 | 0.69 | ADRA2A (0.50) | ADRA2AADRA1ATDP1MEN1KMT2A | |
| SCHEMBL1171680 | 0.69 | TDP1 (0.69) | TDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |