Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899384 | 0.91 | GAA (0.32) | KCNMA1GAAFAAHMGLLF2 | |
| SCHEMBL427962 | 0.84 | KCNMA1 (0.48) | KCNMA1GAAFAAHMGLLKDM4E | |
| SCHEMBL424826 | 0.83 | HCAR3 (0.49) | HPGD | |
| SCHEMBL427200 | 0.82 | NAMPT (0.45) | KCNMA1GAAKDM4EALDH1A1HPGD | |
| SCHEMBL425937 | 0.81 | KCNMA1 (0.51) | KCNMA1ALDH1A1CNR2HPGDSMN1; SMN2 | |
| SCHEMBL425578 | 0.81 | FAAH (0.47) | KCNMA1GAAFAAHMGLLF2 | |
| SCHEMBL7898107 | 0.81 | KCNMA1 (0.43) | KCNMA1GAAKDM4EALDH1A1CNR2 | |
| SCHEMBL424832 | 0.81 | HPGD (0.41) | KDM4EALDH1A1HPGDPOLBMAPT | |
| SCHEMBL426009 | 0.80 | GAA (0.46) | KCNMA1GAAFAAHMGLLKDM4E | |
| SCHEMBL425936 | 0.79 | KCNMA1 (0.39) | KCNMA1GAAFAAHMGLLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |