Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906239 | 0.91 | KCNMA1 (0.37) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL425936 | 0.86 | KCNMA1 (0.39) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL427663 | 0.84 | FAAH (0.36) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL444875 | 0.83 | HCAR3 (0.40) | GAAHPGDFAAHMGLLMGAM | |
| SCHEMBL425919 | 0.82 | HDAC3 (0.43) | GAAKDM4ESMN1; SMN2CNR2HSD17B10 | |
| SCHEMBL426089 | 0.82 | NAMPT (0.38) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL424689 | 0.81 | KCNMA1 (0.42) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL425578 | 0.81 | FAAH (0.47) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL426102 | 0.81 | FAAH (0.42) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL426009 | 0.80 | GAA (0.46) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |