Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ADA | P00813 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585940 | 0.86 | L3MBTL1 (0.41) | L3MBTL1PARP15PARP10SMPD1CETP | |
| SCHEMBL7919811 | 0.81 | NFKB1 (0.55) | NFKB1BLMPMP22 | |
| SCHEMBL5704545 | 0.80 | SMPD1 (0.48) | L3MBTL1PARP15PARP10SMPD1CETP | |
| SCHEMBL7906188 | 0.76 | PDE4B (0.56) | NFKB1BLMPMP22ADRB2DRD2 | |
| SCHEMBL7914446 | 0.76 | NFKB1 (0.60) | NFKB1BLMPMP22SMPD1CYP3A4 | |
| SCHEMBL7906172 | 0.75 | NFKB1 (0.53) | NFKB1BLMPMP22 | |
| SCHEMBL15921910 | 0.75 | NFKB1 (0.75) | NFKB1BLMPMP22L3MBTL1TP53 | |
| SCHEMBL7148550 | 0.75 | NFKB1 (0.75) | NFKB1BLMPMP22L3MBTL1TP53 | |
| SCHEMBL29633151 | 0.75 | NFKB1 (0.75) | NFKB1BLMPMP22L3MBTL1TP53 | |
| SCHEMBL1966507 | 0.75 | NFKB1 (0.75) | NFKB1BLMPMP22L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |