Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353239 | 0.79 | CA1 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5562243 | 0.79 | L3MBTL1 (0.67) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3867855 | 0.77 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5963342 | 0.76 | FABP4 (0.76) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3687291 | 0.74 | L3MBTL1 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL561968 | 0.73 | NPSR1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL17101162 | 0.73 | L3MBTL1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL31066637 | 0.73 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11448202 | 0.73 | L3MBTL1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28192865 | 0.72 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10448632-B2 | Control of plant stress tolerance, water use efficiency and gene expression using novel ABA receptor synthetic agonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-22 | — | — | US | disclosed |
| US-6194498-B1 | AROMATIC SULFONAMIDES AND ETHER AROMATIC SULFONAMIDES | PPG INDUSTRIES OHIO, INC. | 2001-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10448632-B2 | Control of plant stress tolerance, water use efficiency and gene expression using novel ABA receptor synthetic agonists | NPBWR1, AVPR1A, AAK1 | CA1 4287/4885CA2 3119/4885MMP1 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.