Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | FGB | P02675 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746858 | 0.93 | FABP4 (0.68) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL5562243 | 0.92 | L3MBTL1 (0.67) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL4747454 | 0.91 | FABP4 (0.66) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL8576092 | 0.91 | MAPT (0.69) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL7511658 | 0.87 | FABP4 (0.61) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL11560895 | 0.87 | FABP4 (0.61) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL7517048 | 0.87 | FABP4 (0.61) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL3687291 | 0.86 | L3MBTL1 (0.61) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL18553817 | 0.86 | CA2 (0.60) | FABP4L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL11495820 | 0.86 | FABP4 (0.59) | FABP4L3MBTL1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390896-A1 | Polyamine Prodrugs And Polyamine Prodrug Formulations | UNIV NEBRASKA (US) | 2020-12-17 | — | — | US | claimed |
| WO-2019173446-A1 | POLYAMINE PRODRUGS AND POLYAMINE PRODRUG FORMULATIONS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2019-09-12 | — | — | WO | claimed |
| US-20200390896-A1 | Polyamine Prodrugs And Polyamine Prodrug Formulations | UNIV NEBRASKA (US) | 2020-12-17 | — | — | US | disclosed |
| US-20130137772-A1 | HYDROXYPOLYAMINE SALTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2013-05-30 | — | — | US | disclosed |
| US-7094808-B2 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-08-22 | — | — | US | disclosed |
| US-20040131574-A1 | Method and composition for the control of hair growth | FLORIDA, UNIVERSITY OF | 2004-07-08 | — | — | US | disclosed |
| US-20030100615-A1 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2003-05-29 | — | — | US | disclosed |
| US-20020143068-A1 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-10-03 | — | — | US | disclosed |
| WO-2002062341-A1 | METHOD AND COMPOSITION FOR THE CONTROL OF HAIR GROWTH | UNIVERSITY OF FLORIDA (US) | 2002-08-15 | — | — | WO | disclosed |
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | disclosed |
| US-6342534-B1 | BRIDGING GROUPS MAINTAIN DISTANCE BETWEEN NITROGEN ATOMS BINDING VIA ELECTROSTATIC INTERACTION TO COUNTER-ANIONS; ANTITUMOR,ANTICARCINOGENIC AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2002-01-29 | — | — | US | disclosed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |
| US-6184232-B1 | AMINE ADDUCT WHICH COMPETETIVELY BINDS WITH TARGET CELL COUNTERION AND FUNCTIONS DIFFERENTLY COMPARED TO NATURAL INTRACELLULAR POLYAMINES; ANTICARCINOGENIC AGENTS | UNIVERSITY OF FLORIDA | 2001-02-06 | — | — | US | disclosed |
| US-5886051-A | MODULATORS OF THE N-METHYLASPARTIC ACID RECEPTOR; AGONISTS AND ANTAGONISTS; ALZHEIMER'S DISEASE; COGNITION ACTIVATORS; ACYCLIC AND CYCLIC COMPOUNDS HAVING TWO OR MORE SECONDARY AMINES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1999-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040131574-A1 | Method and composition for the control of hair growth | ODC1, OTC, OAT | FABP4 1715/4885L3MBTL1 2888/4885LMNA 3247/4885 |
| US-20030100615-A1 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment | SLC7A1, SRM, SLC1A5 | FABP4 3950/4885L3MBTL1 2888/4885LMNA 1538/4885 |
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | SRM, SLC7A1, CATSPER1 | FABP4 3667/4885L3MBTL1 3921/4885LMNA 3705/4885 |
| US-20130137772-A1 | HYDROXYPOLYAMINE SALTS | ALK, ALKBH3, HRH3 | FABP4 3785/4885L3MBTL1 2607/4885LMNA 3109/4885 |
| US-20020143068-A1 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment | SLC7A1, SRM, SLC1A5 | FABP4 3950/4885L3MBTL1 2888/4885LMNA 1538/4885 |
| US-20200390896-A1 | Polyamine Prodrugs And Polyamine Prodrug Formulations | SRM, SMS, S1PR1 | FABP4 4695/4885L3MBTL1 1737/4885LMNA 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.