Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763188 | 0.73 | APOB (0.34) | — | |
| SCHEMBL4392500 | 0.71 | KDM1A (0.41) | KDM4EKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL4392496 | 0.71 | KDM1A (0.41) | KDM4EKDM1AMAOAMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL7906091 | 0.71 | KDM1A (0.40) | KDM4EKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL13280435 | 0.67 | MAOA (0.55) | KDM4EKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL5539196 | 0.66 | MAOA (0.61) | KDM4EKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL29785655 | 0.66 | MAOA (0.61) | KDM4EKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL662711 | 0.66 | MAOA (0.57) | KDM1AMAOAMAOBALDH1A1HPGD | |
| SCHEMBL1732541 | 0.66 | MAOA (0.61) | KDM4EKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL7907542 | 0.65 | GRIN2B (0.66) | KDM1AMAOAMAOBALDH1A1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005767-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2001-01-25 | — | — | WO | claimed |
| US-6197798-B1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN | NOVARTIS AG (CH) | 2001-03-06 | — | — | US | disclosed |