Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355483 | 0.82 | HPGD (0.36) | HPGDLMNATSHRALDH1A1MAPT | |
| SCHEMBL7907462 | 0.80 | HTR2A (0.38) | HPGDLMNAHTT | |
| SCHEMBL3665645 | 0.76 | APOBEC3G (0.36) | HPGDLMNATSHRALDH1A1MAPT | |
| SCHEMBL21609892 | 0.76 | HPGD (0.47) | HPGDLMNATSHRALDH1A1MAPT | |
| SCHEMBL7900560 | 0.74 | KMT2A (0.44) | HPGDLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16769029 | 0.74 | HPGD (0.46) | HPGDLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL9359552 | 0.74 | HPGD (0.37) | HPGDLMNATSHRALDH1A1MAPT | |
| SCHEMBL7910515 | 0.73 | FAAH (0.39) | LMNAMAPTHTT | |
| SCHEMBL7907310 | 0.72 | THRB (0.46) | HPGDLMNAALDH1A1MAPT | |
| SCHEMBL16769030 | 0.72 | HPGD (0.46) | HPGDLMNAMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5178790-A | With excellent steepness of characteristics | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-01-12 | — | — | US | disclosed |