Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910515 | 0.92 | FAAH (0.39) | HTR2AKMT2AMEN1MAPK1HTT | |
| SCHEMBL7900560 | 0.87 | KMT2A (0.44) | KMT2AMEN1EPHX2HPGDLMNA | |
| SCHEMBL7907310 | 0.84 | THRB (0.46) | KMT2AMEN1EPHX2HPGDLMNA | |
| SCHEMBL8413202 | 0.81 | KMT2A (0.37) | HTR2AKMT2AMEN1MAPK1HTT | |
| SCHEMBL7908374 | 0.80 | HPGD (0.37) | HTTHPGDLMNA | |
| SCHEMBL7900571 | 0.80 | KMT2A (0.42) | KMT2AMEN1EPHX2HPGDLMNA | |
| SCHEMBL7900609 | 0.79 | THRB (0.46) | KMT2AMEN1EPHX2HPGDLMNA | |
| SCHEMBL8410662 | 0.76 | FAAH (0.37) | HTR2AKMT2AMEN1MAPK1HTT | |
| SCHEMBL27463155 | 0.74 | HPGD (0.43) | KMT2AMEN1HTTHPGDLMNA | |
| SCHEMBL9149055 | 0.72 | CETP (0.40) | KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |