Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900571 | 0.93 | KMT2A (0.42) | KMT2AMEN1THRBPLA2G1BATG4B | |
| SCHEMBL7907310 | 0.92 | THRB (0.46) | KMT2AMEN1THRBCYP1A2CYP3A4 | |
| SCHEMBL7900609 | 0.87 | THRB (0.46) | KMT2AMEN1THRBCYP1A2CYP3A4 | |
| SCHEMBL7907462 | 0.87 | HTR2A (0.38) | KMT2AMEN1HPGDLMNAEPHX2 | |
| SCHEMBL8413818 | 0.81 | KMT2A (0.42) | KMT2AMEN1THRBPLA2G1BATG4B | |
| SCHEMBL7910515 | 0.79 | FAAH (0.39) | KMT2AMEN1MAPTLMNAEPHX2 | |
| SCHEMBL8413150 | 0.77 | KMT2A (0.41) | KMT2AMEN1THRBPLA2G1BATG4B | |
| SCHEMBL7908374 | 0.74 | HPGD (0.37) | HPGDMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8413623 | 0.74 | THRB (0.44) | KMT2AMEN1THRBCYP1A2CYP3A4 | |
| SCHEMBL23496620 | 0.73 | THRB (0.52) | KMT2AMEN1THRBCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |