Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908461 | 0.89 | HRH1 (0.37) | HPGDTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL7903985 | 0.87 | KDM4E (0.34) | RAB9ASMN1; SMN2HPGDTSHRHSD17B10 | |
| SCHEMBL7902622 | 0.87 | KDM4E (0.36) | RAB9ANPC1HPGDTSHRHSD17B10 | |
| SCHEMBL7904717 | 0.86 | MAOB (0.33) | KDM4EALDH1A1 | |
| SCHEMBL7896519 | 0.86 | KDM4E (0.31) | KDM4EALDH1A1 | |
| SCHEMBL7902606 | 0.82 | KDM4E (0.36) | RAB9ANPC1HPGDTSHRHSD17B10 | |
| SCHEMBL7902631 | 0.81 | RAB9A (0.38) | RAB9ASMN1; SMN2ALOX15NPC1HPGD | |
| SCHEMBL7905809 | 0.79 | KDM4E (0.36) | HPGDTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL7905780 | 0.77 | HRH3 (0.40) | HPGDTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL7903964 | 0.77 | HTR1B (0.34) | SMN1; SMN2HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |