Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | LDLR | P01130 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918313 | 0.89 | ALDH1A1 (0.36) | FNTAFNTB | |
| SCHEMBL7908652 | 0.81 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL7918697 | 0.81 | BRS3 (0.37) | FNTAFNTBBRS3MYCMCL1 | |
| SCHEMBL7908683 | 0.80 | BRS3 (0.36) | FNTAFNTBBRS3MYCMCL1 | |
| SCHEMBL7918595 | 0.77 | FNTA (0.40) | FNTAFNTBBRS3 | |
| SCHEMBL7921854 | 0.76 | BRS3 (0.38) | FNTAFNTBBRS3MYCMCL1 | |
| SCHEMBL8678148 | 0.72 | FNTA (0.37) | FNTAFNTBBRS3LDLR | |
| SCHEMBL6627774 | 0.72 | FNTA (0.44) | FNTAFNTBBRS3 | |
| SCHEMBL7862461 | 0.70 | FNTA (0.43) | FNTAFNTBBRS3 | |
| SCHEMBL6624997 | 0.70 | FNTA (0.52) | FNTAFNTBBRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |