Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918697 | 0.92 | BRS3 (0.37) | FNTAFNTBBRS3 | |
| SCHEMBL7921829 | 0.90 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL7915090 | 0.88 | MYC (0.39) | LTB4R2 | |
| SCHEMBL7921854 | 0.87 | BRS3 (0.38) | FNTAFNTBBRS3 | |
| SCHEMBL7918230 | 0.83 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7918851 | 0.80 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL7908683 | 0.77 | BRS3 (0.36) | FNTAFNTBBRS3 | |
| SCHEMBL7917806 | 0.77 | CNR1 (0.41) | LTB4R2 | |
| SCHEMBL7916606 | 0.77 | ALDH1A1 (0.37) | FNTAFNTB | |
| SCHEMBL7908677 | 0.77 | FNTA (0.36) | FNTAFNTBBRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |