Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918595 | 0.92 | FNTA (0.40) | BRS3FNTAFNTB | |
| SCHEMBL7921854 | 0.91 | BRS3 (0.38) | BRS3FNTAFNTBMYCMCL1 | |
| SCHEMBL7908683 | 0.82 | BRS3 (0.36) | BRS3FNTAFNTBMYCMCL1 | |
| SCHEMBL7921829 | 0.82 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL7908677 | 0.81 | FNTA (0.36) | BRS3FNTAFNTBMYCMCL1 | |
| SCHEMBL7915328 | 0.81 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL7916606 | 0.80 | ALDH1A1 (0.37) | FNTAFNTB | |
| SCHEMBL7915090 | 0.78 | MYC (0.39) | MYCMCL1PPARG | |
| SCHEMBL7908805 | 0.78 | ALDH1A1 (0.36) | FNTAFNTB | |
| SCHEMBL7918230 | 0.76 | FNTA (0.64) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |