Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802961 | 0.83 | CTSS (0.69) | KLK5CTSSCTSKCTSBACE | |
| SCHEMBL1826757 | 0.83 | CTSS (0.69) | KLK5CTSSCTSKCTSBACE | |
| SCHEMBL10033679 | 0.83 | CTSS (0.69) | KLK5CTSSCTSKCTSBACE | |
| SCHEMBL7061529 | 0.80 | HDAC1 (0.63) | KLK5CTSSCTSKEPHX2CTSB | |
| SCHEMBL31584535 | 0.80 | CTSS (0.69) | KLK5CTSSCTSKCTSBACE | |
| SCHEMBL5630007 | 0.80 | CTSS (0.69) | KLK5CTSSCTSKCTSBACE | |
| SCHEMBL12889741 | 0.79 | CTSS (0.52) | KLK5CTSSCTSKCTSBACE | |
| SCHEMBL84524 | 0.79 | KLK5 (0.72) | KLK5CTSSCTSKEPHX2CTSB | |
| SCHEMBL6292728 | 0.79 | KLK5 (0.72) | KLK5CTSSCTSKEPHX2CTSB | |
| SCHEMBL21473748 | 0.79 | KLK5 (0.72) | KLK5CTSSCTSKEPHX2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |