Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LDLR | P01130 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921832 | 0.81 | FNTA (0.37) | FNTAFNTB | |
| SCHEMBL628805 | 0.80 | BACE1 (0.40) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL629208 | 0.79 | BACE1 (0.40) | ALDH1A1 | |
| SCHEMBL7916606 | 0.78 | ALDH1A1 (0.37) | FNTAFNTBKDM4EALDH1A1HPGD | |
| SCHEMBL7869014 | 0.77 | FNTA (0.42) | FNTAFNTBCASRKDM4EALDH1A1 | |
| SCHEMBL629649 | 0.76 | FNTA (0.37) | FNTAFNTB | |
| SCHEMBL7908805 | 0.76 | ALDH1A1 (0.36) | FNTAFNTBKDM4EALDH1A1HPGD | |
| SCHEMBL6625288 | 0.75 | FNTA (0.42) | FNTAFNTB | |
| SCHEMBL7905228 | 0.75 | FNTA (0.37) | FNTAFNTBCASR | |
| SCHEMBL628906 | 0.75 | FNTA (0.43) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |