Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571688 | 0.88 | TET2 (0.46) | TET2CA2CHRM1POLBKMT2A | |
| SCHEMBL1271332 | 0.75 | TET2 (0.46) | TET2GSTP1CHRM1TP53POLB | |
| Ammonia Solution, Strong SCHEMBL591415 | 0.73 | TET2 (0.45) | TET2GSTP1CHRM1TP53POLB | |
| SCHEMBL2530974 | 0.73 | POLB (0.40) | TET2GSTP1CHRM1TP53POLB | |
| SCHEMBL10693669 | 0.72 | POLB (0.37) | TET2GSTP1CHRM1TP53POLB | |
| SCHEMBL3761809 | 0.71 | GSTP1 (0.46) | CA2GSTP1CA1CA9 | |
| SCHEMBL14008404 | 0.71 | POLB (0.35) | TET2CHRM1POLBKMT2AALDH1A1 | |
| SCHEMBL2728455 | 0.70 | MEN1 (0.41) | CA2POLBKMT2ACA1CA9 | |
| SCHEMBL7752552 | 0.68 | RORA (0.46) | CA2TP53POLBCA1CA9 | |
| SCHEMBL1893522 | 0.68 | HDAC4 (0.45) | CHRM1POLBKMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197258-B1 | DETECTOR FOR DETERMINING AQUEOUS METAL ION CONCENTRATION INCLUDING A PHOTOLUMINESCENT LABEL BOUND TO AN ANALYTE BINDING MACROMOLECULE OF HUMAN APOCARBONIC ANHYDRASE OR DERIVATIVE | UNIVERSITY OF MARYLAND, BALTIMORE | 2001-03-06 | — | — | US | disclosed |