Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501666 | 0.84 | ACHE (0.37) | ACHECYP3A4MAPTALDH1A1KDM4E | |
| SCHEMBL20133820 | 0.81 | — | — | |
| SCHEMBL2045702 | 0.74 | ALDH1A1 (0.35) | ACHECYP3A4ALDH1A1TRPA1 | |
| SCHEMBL7915807 | 0.73 | CYP3A4 (0.46) | ACHECYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL28669355 | 0.73 | CYP3A4 (0.57) | ACHECYP3A4MAPTALDH1A1KDM4E | |
| SCHEMBL17402435 | 0.73 | CYP3A4 (0.57) | ACHECYP3A4MAPTALDH1A1KDM4E | |
| SCHEMBL20133598 | 0.71 | — | — | |
| SCHEMBL1109757 | 0.70 | RAPGEF4 (0.38) | ACHEMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL31305641 | 0.69 | ACHE (0.50) | ACHECYP3A4MAPTALDH1A1KDM4E | |
| SCHEMBL393790 | 0.69 | ACHE (0.50) | ACHECYP3A4MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211328-B1 | IN PRESENCE OF AN ACID | GUN EI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-04-03 | — | — | US | disclosed |