Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | MDH1 | P40925 | 1/20 | 0.34 |
| ▸ | MDH2 | P40926 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15845321 | 0.80 | CYP3A4 (0.58) | SMN1; SMN2CYP3A4ACACBALDH1A1MEN1 | |
| SCHEMBL1059941 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL2170360 | 0.74 | CA12 (0.42) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL513003 | 0.72 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL10707563 | 0.72 | ACACB (0.39) | SMN1; SMN2ACACBKDM4EALDH1A1 | |
| SCHEMBL7904973 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP3A4ACACBPOLBAPP | |
| SCHEMBL23091406 | 0.71 | HRH3 (0.51) | HRH3 | |
| SCHEMBL13902305 | 0.70 | CYP3A4 (0.68) | SMN1; SMN2CYP3A4ACACBALDH1A1MEN1 | |
| SCHEMBL1274091 | 0.70 | LTA4H (0.45) | MEN1KMT2AHRH3 | |
| SCHEMBL514644 | 0.69 | L3MBTL1 (0.47) | CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163374-A2 | ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES | Syntrix Biochip, Inc. (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-1163520-A1 | POROUS COATINGS BEARING LIGAND ARRAYS | Syntrix Biochip, Inc. (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000033084-A2 | ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES | SYNTRIX BIOCHIP, INC. (US) | 2000-06-08 | — | — | WO | disclosed |
| WO-2000033078-A1 | POROUS COATINGS BEARING LIGAND ARRAYS | SYNTRIX BIOCHIP, INC. (US) | 2000-06-08 | — | — | WO | disclosed |