SCHEMBL7909660

SCHEMBL7909660

CC1(C)CC(CN)c2cc(I)ccc2O1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10650405 0.84 HTR2C (0.43) TRPV1
SCHEMBL7913673 0.78 HTR2A (0.39) TRPV1
SCHEMBL7909655 0.74 CNR1 (0.40) TRPV1
SCHEMBL7909726 0.74 KCNH2 (0.40)
SCHEMBL7910194 0.73 NCF1 (0.38)
SCHEMBL10652491 0.71 MAPT (0.42)
SCHEMBL10586245 0.68 CYP26A1 (0.42) TRPV1
SCHEMBL10592034 0.68 TLR3 (0.36) TRPV1
SCHEMBL12036000 0.67 MAPT (0.40)
SCHEMBL10593584 0.66 KDM4E (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177449-B1 CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-01-23 US disclosed