Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909723 | 0.79 | HDAC1 (0.41) | KCNH2HDAC1HDAC2HDAC3 | |
| SCHEMBL10650405 | 0.75 | HTR2C (0.43) | — | |
| SCHEMBL6601927 | 0.75 | KCNE1 (0.39) | HDAC1HDAC2HDAC3 | |
| SCHEMBL7909660 | 0.74 | TRPV1 (0.30) | — | |
| SCHEMBL7910194 | 0.66 | NCF1 (0.38) | — | |
| SCHEMBL27710422 | 0.65 | ALDH1A1 (0.55) | KCNH2PGR | |
| SCHEMBL10652491 | 0.64 | MAPT (0.42) | KCNH2PTGS1PGR | |
| Hydrochloric Acid SCHEMBL6561181 | 0.63 | HTR2B (0.46) | — | |
| SCHEMBL27675555 | 0.63 | KCNH2 (0.44) | KCNH2LPLLIPGALOX5PTGS1 | |
| SCHEMBL3249226 | 0.61 | RPS6KB2 (0.57) | KCNH2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |