Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919399 | 0.85 | S100A9 (0.35) | — | |
| SCHEMBL7916846 | 0.78 | CHRNB2 (0.42) | — | |
| SCHEMBL7919587 | 0.72 | CHRNB2 (0.46) | — | |
| SCHEMBL8149329 | 0.72 | PTGS2 (0.42) | PTGS2 | |
| SCHEMBL7917315 | 0.70 | PTGS2 (0.48) | ADORA2APTGS2 | |
| SCHEMBL8118971 | 0.70 | MAPT (0.36) | PTGS2 | |
| SCHEMBL8177172 | 0.69 | NR1I2 (0.35) | PTGS2 | |
| SCHEMBL14823453 | 0.69 | PTGS2 (0.38) | ADORA2APTGS2 | |
| SCHEMBL2114332 | 0.69 | MAPT (0.46) | ADORA2APTGS2 | |
| SCHEMBL29837825 | 0.69 | L3MBTL1 (0.38) | ADORA2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225320-B1 | TREATMENT OF PAIN, INFLAMMATION, MIGRAINE, EMESIS AND POSTTHERPETIC NEURALGIA | MERCK SHARP & DOHME LTD. (GB) | 2001-05-01 | — | — | US | disclosed |