Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470125 | 0.82 | VNN1 (0.34) | SRD5A2HTTNPC1 | |
| SCHEMBL7919391 | 0.81 | NPSR1 (0.38) | MAPTRAB9AHTTHPDMEN1 | |
| SCHEMBL8002517 | 0.81 | TP53 (0.34) | SRD5A2MAPTRAB9AHTTHPD | |
| SCHEMBL7998737 | 0.79 | KLKB1 (0.36) | SRD5A2MAPTRAB9AHTTHPD | |
| SCHEMBL7917708 | 0.75 | CHEK2 (0.35) | CHEK2MEN1KMT2A | |
| SCHEMBL8002706 | 0.74 | LSS (0.34) | MAPTRAB9AHTTMEN1KMT2A | |
| SCHEMBL7917047 | 0.73 | CYP3A4 (0.31) | MEN1KMT2A | |
| SCHEMBL8002345 | 0.73 | AR (0.30) | — | |
| SCHEMBL7917515 | 0.72 | GAA (0.39) | MAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL7990339 | 0.71 | PARP1 (0.34) | MAPTRAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0648760-B1 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0648760-A2 | Triazine derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |