Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 12/20 | 0.41 |
| ▸ | FNTB | P49356 | 12/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905174 | 0.92 | PPARG (0.40) | FNTAFNTBPPARGPPARAFFAR1 | |
| SCHEMBL7905904 | 0.90 | FNTA (0.43) | FNTAFNTB | |
| SCHEMBL7910498 | 0.82 | FNTA (0.42) | FNTAFNTBFFAR1FFAR4 | |
| SCHEMBL7904826 | 0.81 | FNTA (0.42) | FNTAFNTBPPARGPPARAFFAR1 | |
| SCHEMBL7903908 | 0.77 | RXRA (0.41) | FNTAFNTBFFAR1FFAR4S1PR1 | |
| SCHEMBL7904559 | 0.77 | MYC (0.43) | FNTAFNTBPPARGPPARAFFAR1 | |
| SCHEMBL7897588 | 0.76 | FNTA (0.42) | FNTAFNTBPPARGPPARAFFAR1 | |
| SCHEMBL7904841 | 0.76 | FNTA (0.42) | FNTAFNTBPPARGPPARAFFAR1 | |
| SCHEMBL7904816 | 0.76 | FFAR1 (0.42) | FNTAFNTBPPARGPPARAFFAR1 | |
| SCHEMBL7572010 | 0.75 | MYC (0.41) | FNTAFNTBPPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |
| WO-1998050031-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |