Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 4/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922905 | 0.81 | MME (0.48) | SSTR4SSTR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7921872 | 0.79 | EPHX2 (0.50) | SLC6A2SLC6A4SLC6A3SMYD3MMP9 | |
| SCHEMBL7919565 | 0.79 | EPHX2 (0.50) | SLC6A2SLC6A4SLC6A3SMYD3MMP9 | |
| SCHEMBL7919569 | 0.76 | MTNR1A (0.49) | SLC6A2SLC6A4SLC6A3SMYD3 | |
| SCHEMBL7919878 | 0.75 | EPHX1 (0.50) | SSTR4SSTR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19200342 | 0.74 | MAPT (0.54) | PYGLMAPK1CNR1 | |
| SCHEMBL4375995 | 0.73 | SLC6A2 (0.50) | SSTR4SSTR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2172656 | 0.72 | ATM (0.57) | SLC6A2SLC6A4SLC6A3ATMCYP2D6 | |
| SCHEMBL1919144 | 0.70 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3SMYD3ATM | |
| SCHEMBL4372327 | 0.70 | SLC6A2 (0.47) | SSTR4SSTR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054968-A1 | QUINAZOLINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-20 | — | — | WO | disclosed |