Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914033 | 0.91 | HTR2C (0.38) | HTR2CMAPTOPRL1MEN1KMT2A | |
| SCHEMBL9237861 | 0.90 | HTR2C (0.39) | HTR2CMAPTOPRL1MEN1KMT2A | |
| SCHEMBL10611692 | 0.83 | HTR2C (0.53) | HTR2CGAAHPGDGRM2RBP4 | |
| SCHEMBL7913981 | 0.80 | DRD2 (0.35) | HTR2CGAAMAPTOPRL1MEN1 | |
| SCHEMBL7911206 | 0.78 | ALDH1A1 (0.40) | MAPTMEN1KMT2AMAPK1CYP2C9 | |
| SCHEMBL8630544 | 0.77 | CYP1A2 (0.38) | HTR2CGAAMAPTOPRL1MEN1 | |
| SCHEMBL7913987 | 0.76 | ALDH1A1 (0.41) | MAPTMEN1KMT2AMAPK1CYP2C9 | |
| SCHEMBL8630384 | 0.76 | CYP1A2 (0.37) | HTR2CGAAMAPTOPRL1MEN1 | |
| SCHEMBL7903639 | 0.75 | MAPT (0.40) | GAAMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL5676928 | 0.74 | OPRL1 (0.41) | GAAMAPTOPRL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640578-B2 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0640578-B1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0640578-A1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | Chisso Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |