Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237861 | 0.99 | HTR2C (0.39) | HTR2COPRL1CYP2C9RBP4ALDH1A1 | |
| SCHEMBL7911032 | 0.91 | HTR2C (0.36) | HTR2COPRL1CYP2C9RBP4ALDH1A1 | |
| SCHEMBL7913546 | 0.79 | DRD2 (0.37) | HTR2COPRL1CYP2C9DRD3OPRM1 | |
| SCHEMBL7917585 | 0.76 | ALDH1A1 (0.49) | HTR2CCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8632162 | 0.75 | HTR2C (0.39) | HTR2COPRL1CYP2C9RBP4ALDH1A1 | |
| SCHEMBL9239246 | 0.74 | DRD2 (0.36) | HTR2COPRL1CYP2C9DRD3OPRM1 | |
| SCHEMBL7914131 | 0.74 | ALDH1A1 (0.50) | HTR2CCYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10611692 | 0.72 | HTR2C (0.53) | HTR2CRBP4ALDH1A1GRM2DRD3 | |
| SCHEMBL7148263 | 0.72 | OPRL1 (0.44) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL4650755 | 0.72 | CYP2C9 (0.44) | OPRL1CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640578-B2 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0640578-B1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0640578-A1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | Chisso Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |