Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916797 | 0.81 | NNMT (0.35) | MAPT | |
| SCHEMBL7916825 | 0.80 | ACHE (0.35) | MAPT | |
| SCHEMBL7903016 | 0.69 | ADRA2A (0.44) | MAPT | |
| SCHEMBL7916798 | 0.69 | ADRA2A (0.44) | MAPT | |
| SCHEMBL7912936 | 0.68 | ADRA2A (0.45) | MAPT | |
| Dimethylamine SCHEMBL7911323 | 0.68 | ADRA2A (0.42) | MAPT | |
| SCHEMBL7910325 | 0.68 | GRM5 (0.36) | MAPT | |
| Fumaric Acid SCHEMBL8138269 | 0.64 | ADRA2A (0.39) | MAPT | |
| SCHEMBL7911213 | 0.64 | CACNB4 (0.37) | MAPTATM | |
| SCHEMBL927448 | 0.63 | NPC1 (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |