Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 5/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913265 | 0.94 | SIRT2 (0.39) | SIRT2NPY1RAURKARPS6KB1LMNA | |
| SCHEMBL7903219 | 0.85 | LMNA (0.38) | LMNASMN1; SMN2NPSR1MAOBKDM4E | |
| SCHEMBL7916990 | 0.85 | LMNA (0.41) | LMNASMN1; SMN2NPSR1MAOBKDM4E | |
| SCHEMBL7916986 | 0.84 | ALDH1A1 (0.46) | AURKALMNASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL7911558 | 0.84 | ALDH1A1 (0.40) | AURKALMNASMN1; SMN2NPSR1MAOB | |
| Hydrochloric Acid SCHEMBL7911590 | 0.83 | ITGB3 (0.37) | LMNASMN1; SMN2NPSR1MAOBKDM4E | |
| SCHEMBL7903245 | 0.80 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2NPSR1MAOBKDM4E | |
| SCHEMBL7903260 | 0.80 | SMN1; SMN2 (0.39) | AURKALMNASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL7910597 | 0.80 | ALDH1A1 (0.36) | AURKALMNASMN1; SMN2NPSR1MAOB | |
| SCHEMBL7911574 | 0.79 | LMNA (0.43) | AURKALMNASMN1; SMN2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |