Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.36 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916986 | 0.94 | ALDH1A1 (0.46) | ALDH1A1GAAPKMFAAHMGLL | |
| SCHEMBL7910547 | 0.93 | HSD17B10 (0.38) | ALDH1A1GAAPKMFFAR1FAAH | |
| SCHEMBL7903219 | 0.90 | LMNA (0.38) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL7916990 | 0.90 | LMNA (0.41) | LMNASMN1; SMN2NPSR1KDM4ETSHR | |
| SCHEMBL7910595 | 0.90 | L3MBTL1 (0.35) | ALDH1A1GAAPKMFAAHMGLL | |
| Hydrochloric Acid SCHEMBL7911590 | 0.88 | ITGB3 (0.37) | MGLLLMNASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL7910597 | 0.88 | ALDH1A1 (0.36) | ALDH1A1GAAPKMFAAHMGLL | |
| SCHEMBL7911574 | 0.87 | LMNA (0.43) | ALDH1A1GAAPKMFAAHMGLL | |
| SCHEMBL7911545 | 0.85 | CCNA2 (0.38) | ALDH1A1FAAHMGLLLMNASMN1; SMN2 | |
| SCHEMBL7903245 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1FAAHLMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291485-B1 | TREATMENT OF POST-PTCA RESTENOSIS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1002797-A1 | 4,5-DIHYDRO- 1H]-BENZ g]INDAZOLE-3-CARBOXYLIC ACID DERIVATIVES | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2000-05-24 | — | — | EP | disclosed |